Fig. 7.
In vivo BM cell morphologic changes in an APL patient during continuous As2O3 treatment. (A) Promyelocytic leukemic cells before the treatment; (B) myelocyte-like cells on day 21 of treatment; (C and D) “nude nuclear” cells with coarse (C) or condensed (D) nuclei on day 28 of the treatment. Similar changes also appeared in peripheral blood (not shown).
