Fig. 5.
Fig. 5. Immuno-fluorescence analysis of the subcellular localization of PML-RARα/PML in cultured primary APL cells from a patient. (A) Control; (B) 1 μmol/L As2O3 treatment for 12 hours; (C) 1 μmol/L As2O3 treatment for 24 hours. (D) One micromolar As2O3 treatment for 48 hours; (E) 0.1 μmol/L 1 μmol/L As2O3 treatment for 24 hours; (F ) in vivo BM cells on day 15 of treatment.

Immuno-fluorescence analysis of the subcellular localization of PML-RARα/PML in cultured primary APL cells from a patient. (A) Control; (B) 1 μmol/L As2O3 treatment for 12 hours; (C) 1 μmol/L As2O3 treatment for 24 hours. (D) One micromolar As2O3 treatment for 48 hours; (E) 0.1 μmol/L 1 μmol/L As2O3 treatment for 24 hours; (F ) in vivo BM cells on day 15 of treatment.

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