BM biopsy sample from patient with myeloma with in situ hybridization for KSHV ORF 72. Biotin-labeled probe is localized to BM stromal cells (arrowheads, brown) (left). Immunohistochemical stain for fascin (red) shows a similar distribution of BM dendritic cells within the stroma (right). Hematoxylin counterstain; original magnification × 400.