Focal MR pattern of abnormal marrow in a 48-year-old man with multiple myeloma: T1-weighted (500/10, TR/TE) (A), T2-weighted, fat-suppressed fast spin echo (5000/96, TR/TE, ET 16) (B), and enhanced T1-weighted (500/10, TR/TE) (C) sagittal MR images of the lumbar spine. Focal lesions (arrows) in L2 and S1 are dark in (A), bright in (B), and in (C) they enhance and become almost imperceptible from the uninvolved marrow.