Induction of apoptosis in culture of total and T-cell–depleted BM cells from a normal subject and from a patient with CML stimulated by anti-Fas MoAb. (A) and (B) Ethidium bromide staining of agarose gel after electrophoresis of low–molecular-weight DNA. DNA was extracted from 1 × 10⁶ total BM cells (A) and T-cell–depleted BM cells (B) after culture for 48 hours in the presence of the indicated concentrations of IFN-α. Anti-Fas MoAb was used at a concentration of 1 μg/mL.