Effect of IL-10 on IL-12 p35 and p40 mRNA accumulation in monocytes. Monocyte-enriched adherent cells were preincubated for 4 hours with recombinant IL-10 at 0, 15, 30, and 90 U/mL; activated with SAC for 4 hours and finally harvested for mRNA assay. Each value represents the mean ± SEM of triplicate culture samples.