Fig. 7.
Fig. 7. Effect of neutralizing anti–IL-10 on HIV recombinant gp120-inhibited IL-12 p40 secretion by monocytes. Monocyte-enriched adherent cells were pretreated with HIV recombinant gp120 and different concentrations of monoclonal neutralizing anti–IL-10 for 24 hours and then activated by SAC for 24 hours. Supernatants were harvested for IL-12 p40 assay. Each value represents the mean ± SEM of triplicate culture samples.

Effect of neutralizing anti–IL-10 on HIV recombinant gp120-inhibited IL-12 p40 secretion by monocytes. Monocyte-enriched adherent cells were pretreated with HIV recombinant gp120 and different concentrations of monoclonal neutralizing anti–IL-10 for 24 hours and then activated by SAC for 24 hours. Supernatants were harvested for IL-12 p40 assay. Each value represents the mean ± SEM of triplicate culture samples.

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