Fig. 6.
Effect of dgRTA on the permeability of HUVE and HUV-EC-C monolayers. HUV-EC-C and HUVE monolayers were cultured and permeability was assessed as in Fig 3. Passage 19 HUV-EC-C (circles) or pooled passage 4 HUVE monolayers (diamonds) were either left untreated (open symbols) or treated with dgRTA (10−8 mol/L; 0.3 μg/mL; solid symbols). To facilitate comparing results derived from the different cell types, the data are expressed as the mean fold change in fluid flux relative to pretreatment fluid flux. The mean pretreatment fluid flux values for HUV-EC-C and HUVE cells in this experiment were 4.2 and 10.5 (μL/min)/cm2, respectively.
