Effect of anti–IL-6 receptor antibody (hPM1) in mice IV transplanted with KPMM2 cells. hPM1 was injected at 0.2 mg/mouse on day 1. (A) Serum M-protein level. (B) Plasma ionized calcium level on day 34. (Control; n = 12, hPM1; n = 10) (C) Life span. Control ( — ; n = 9); hPM1 (⋅⋅⋅; n = 6).