American Society of Hematology

Fig. 3.

Inhibition by HLE and Cat G of PGI2 synthesis induced by thrombin in ECs. PGI2 synthesis was measured from supernatants of confluent HUVEC monolayers preincubated for 30 minutes with increasing concentrations of HLE or Cat G before stimulation with 1 nmol/L thrombin. Each data point is expressed as the percentage of PGI2 synthesis measured from control, nonpretreated cells activated by thrombin and corresponds to the mean ± SEM of four to five distinct experiments.

Inhibition by HLE and Cat G of PGI₂ synthesis induced by thrombin in ECs. PGI₂ synthesis was measured from supernatants of confluent HUVEC monolayers preincubated for 30 minutes with increasing concentrations of HLE or Cat G before stimulation with 1 nmol/L thrombin. Each data point is expressed as the percentage of PGI₂ synthesis measured from control, nonpretreated cells activated by thrombin and corresponds to the mean ± SEM of four to five distinct experiments.

This Feature Is Available To Subscribers Only