Fig. 6.
![Fig. 6. Effect of ADP addition on collagen plus thrombin-induced platelet prothrombinase and [Ca2+]i . Prothrombinase activity (top, A and B), and average [Ca2+]i (bottom, C and D) in platelets stimulated by collagen plus thrombin in the presence and absence of stirring, with 5 μmol/L ADP (+ADP) or elution buffer (−ADP) added 30 seconds after stimulation. Results (mean ± SE) are shown for five normal subjects (N) and seven δ-SPD-HPS patients. P values: **<.01, ***<.001.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/89/5/10.1182_blood.v89.5.1599/3/bl_0049f6.jpeg?Expires=1724155983&Signature=r28eeSKqUBOKE8VMwNoCLF1ZP78Y907xtDdRDiTHm0uCjcvgyxQvOtliXMJk5yq9iSotoyNxLy9YrUnuDgh1xJR2byCIkBdtY8YdTCSpgJl4ifgFtXw25SyL0Sb4OM8-el90sfBuOpD2K3bHE1FNVkaQqYFo0MZ0AEGMocKAz5NHR2cqNuaNOVpB4nnDMIl5v9QEG9EMjqTtGyMlj5XWmkeTXofRRWHuxVSm9C6ENajwjJ1pYd-Y3f~3kgAgsNDrNgEtlyunPhelnwkP~RDSOJBDkp~4z47EAHQ-uV-M5QjJaCrCHO2NQfyk022R2zLh8e7jxqZwUmh4WNmwICDTrA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of ADP addition on collagen plus thrombin-induced platelet prothrombinase and [Ca2+]i . Prothrombinase activity (top, A and B), and average [Ca2+]i (bottom, C and D) in platelets stimulated by collagen plus thrombin in the presence and absence of stirring, with 5 μmol/L ADP (+ADP) or elution buffer (−ADP) added 30 seconds after stimulation. Results (mean ± SE) are shown for five normal subjects (N) and seven δ-SPD-HPS patients. P values: **<.01, ***<.001.
