Fig. 3.
![Fig. 3. Collagen plus thrombin-induced Ca2+ responses. Changes in [Ca2+]i during stimulation of fura-2–loaded GFP with collagen plus thrombin, with (A) or without (B) stirring in 8 normal subjects, 4 patients with thrombasthenia (TSA), and 6 δ-SPD-HPS patients (HPS). The values (mean ± SE) plotted for the first 3 minutes are the mean [Ca2+]i levels at the times indicated, while the values plotted from 4 to 10 minutes are the average [Ca2+]i values measured over the previous minute, calculated as described in Materials and Methods. [Ca2+]i measurements were obtained at 2-second intervals. Agonists were added at 65 seconds.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/89/5/10.1182_blood.v89.5.1599/3/bl_0049f3.jpeg?Expires=1722765440&Signature=DvjGv2dQ0c8HwPcvXKXjDLPmhiNHcisHwdDDSYQpiaHCC4JACsPvqpge5VZxCg3FCtQIO5t1iTVrvQRGwg0mMAtSr1kClbUgXs65ncarA39Ew2e2F5e11AzKZpODA-hwrr0THrehTqR3WWVlfJyo370RTF210KUIozXpCRTaY61bHVjK4lF427tGQ064bhU9n9lmwxmalnB2Z~RruDk57ctMjw~cfLIH4L5OTtdMg5-T42FHxS2DvlgrxLdtW34-VbZqkS~nCBPP4bUiAqWlKYsPiIRHAYrDtj2jrhQE3ithX1ykR9SQMiKu5XYIHg1Jyh5vPXffBYX5-GhhOM017w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Collagen plus thrombin-induced Ca2+ responses. Changes in [Ca2+]i during stimulation of fura-2–loaded GFP with collagen plus thrombin, with (A) or without (B) stirring in 8 normal subjects, 4 patients with thrombasthenia (TSA), and 6 δ-SPD-HPS patients (HPS). The values (mean ± SE) plotted for the first 3 minutes are the mean [Ca2+]i levels at the times indicated, while the values plotted from 4 to 10 minutes are the average [Ca2+]i values measured over the previous minute, calculated as described in Materials and Methods. [Ca2+]i measurements were obtained at 2-second intervals. Agonists were added at 65 seconds.
