Fig. 6.
![Fig. 6. Accumulation of 3[H]-daunorubicin into cytoplasts prepared from (⊡) U-A10 and (♦) U-937 cells. Cytoplasts were exposed to 0 to 750 ng/mL of 3[H]-daunorubicin for 1 hour before terminating drug accumulation by pelleting through silicone oil. Shown is a plot of the mean (± the standard error) daunorubicin accumulation into cytoplasts versus external drug concentration for three experiments each performed in duplicate. The differences were statistically significant at 500 (P < .005) and 750 ng/mL (P < .01) of daunorubicin.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/89/10/10.1182_blood.v89.10.3745/3/bl_0051f6.jpeg?Expires=1723257150&Signature=rOlsFTsBCkx584cos3LHhQM1ffuTjmqEIR0SIyrR1oDlm5fWUhZ6lqZgQCRAlbJS1gOWQOvAhhSf~O7hxwemPMqj80ZFxL86589~3eGUf5mPtRm~iiewzXj3A~Bb5bRzXFeTTzvVxcInsh9shzI83TGG-Kfis-XSxoDrF-MP2wRd10mUjM-tYqtvDTelS5QxRLG~PNrrfWeOZZ4n64Z~xcI5CPiTc3NZm5LLYgGDSd2mIC88h5sDPMU58OVvLZHJ3Prx1usbDgrX5AaLVzoQBfuBQo5bNN19U3erS0XP0msnroykYB-cNit2MY1tJAjnSlboB9MvbbAkXA2wFHmJ6w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Accumulation of 3[H]-daunorubicin into cytoplasts prepared from (⊡) U-A10 and (♦) U-937 cells. Cytoplasts were exposed to 0 to 750 ng/mL of 3[H]-daunorubicin for 1 hour before terminating drug accumulation by pelleting through silicone oil. Shown is a plot of the mean (± the standard error) daunorubicin accumulation into cytoplasts versus external drug concentration for three experiments each performed in duplicate. The differences were statistically significant at 500 (P < .005) and 750 ng/mL (P < .01) of daunorubicin.
