Thrombin generation by apoptotic VSMCs generated in 0% and 10% serum. VSMCs derived from human coronary atherosclerotic plaques (HASMC-66 E1A), which apoptose even in the presence of serum, were grown to confluence. Thrombin generation was measured for apoptotic HASMC-66 E1A cells generated in 0% (□) and 10% (⋄) serum. For comparison, the thrombin-generation curve for buffer C is also shown (○).