Figure 1.
![Plasma hepcidin and derivative indices in iron metabolism disorders. (A-C) Plasma hepcidin and derivative indices of IRIDA patients with biallelic TMPRSS6 mutations (mut/mut [n = 44]), their heterozygous relatives (mut/+ [n = 59]), wild-type controls (+/+ [n = 35]), and TMPRSS6-mutation-negative cID/A patients (cID [n = 66]). Box and whisker plots present the quartiles (box), and the 10th and 90th percentiles (whiskers). (D) Receiver operating characteristic curve analysis comparing hepcidin, ferritin, and their derivative indices in the TMPRSS6mut/mut and cID groups (see also supplemental Tables 2 and 3; supplemental Figure 2).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/132/4/10.1182_blood-2017-03-773028/4/blood773028f1.jpeg?Expires=1721645804&Signature=YtyNSzykb2SCu4YyEd8f0OYXl-QM47V1GYx2LlNZPixSQVAFT1hJpUEZyXK~hNHAWQZityZ2~66JeMNenJhYfDpDHNrFyB5aA6KEMWeR8QynWVfkUcbKsupg491i7bQoPVPsC-RsdnwTSQvSCVptOjhG9jrq5Al3QV7561bKTJgAoPJUfQcDXg0cAzga0V4M7iwlkfk9dENj-bjAZqe6sRqnd2TLJ4Q4XgNj9W1AsaeZ4cHcCqI72m7wzYK53ibxL4hl3ZV-C~35wZ0G-w2iNLxIHux9pG-z0ghdE4lKl~2d~9iwTUM1rX-aqs2ztJOLvc75vAdzjQCnxXDF5PPHFQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Plasma hepcidin and derivative indices in iron metabolism disorders. (A-C) Plasma hepcidin and derivative indices of IRIDA patients with biallelic TMPRSS6 mutations (mut/mut [n = 44]), their heterozygous relatives (mut/+ [n = 59]), wild-type controls (+/+ [n = 35]), and TMPRSS6-mutation-negative cID/A patients (cID [n = 66]). Box and whisker plots present the quartiles (box), and the 10th and 90th percentiles (whiskers). (D) Receiver operating characteristic curve analysis comparing hepcidin, ferritin, and their derivative indices in the TMPRSS6mut/mut and cID groups (see also supplemental Tables 2 and 3; supplemental Figure 2).
