The immune microenvironment of DTFL and LSTFL. (A) Volcano plot indicating differentially expressed genes in DTFL and LSTFL. Chemokine and cytokine genes are highlighted in red. Genes with a log2 fold change >1 and P value <.02 are labeled. (B) Heat map and unsupervised, hierarchical clustering for genes associated with chronic inflammation. Genes associated with chronic inflammation separate DTFL and LSTFL into 2 discrete clusters.