Figure 7.
Figure 7. Mature KIR+ NK cells that are spared by PT-Cy can protect against posttransplantation disease relapse. (A) Absolute counts of circulating NK cells, (B) absolute counts of CD57+CD16+KIR+NKG2C+ memory-like NK cells, (C) percentage of CD62L+ NK cells, and (D) percentage of KIR+ NK cells were determined in samples collected at day 30 after HSCT from 59 patients who received haploidentical HSCT followed by PT-Cy at OSR. For each of these parameters, dot plots to the left of the figure display the distribution in the patient cohort, discriminating between patients with values above (red dots and background) or below (blue dots and background) the median. Curves display the cumulative incidence of disease relapse (center panels) and PFS (right panels) in each subgroup. P values reported in each panel corner are relative to univariate comparisons performed using Gray's test (for cumulative incidence of relapse) or log-rank test (for PFS).

Mature KIR+NK cells that are spared by PT-Cy can protect against posttransplantation disease relapse. (A) Absolute counts of circulating NK cells, (B) absolute counts of CD57+CD16+KIR+NKG2C+ memory-like NK cells, (C) percentage of CD62L+ NK cells, and (D) percentage of KIR+ NK cells were determined in samples collected at day 30 after HSCT from 59 patients who received haploidentical HSCT followed by PT-Cy at OSR. For each of these parameters, dot plots to the left of the figure display the distribution in the patient cohort, discriminating between patients with values above (red dots and background) or below (blue dots and background) the median. Curves display the cumulative incidence of disease relapse (center panels) and PFS (right panels) in each subgroup. P values reported in each panel corner are relative to univariate comparisons performed using Gray's test (for cumulative incidence of relapse) or log-rank test (for PFS).

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