Serum iron indices at diagnosis. (A) SF (μg/L) and (B) TS (%) at diagnosis are shown for patients with HJV-, HAMP-, TFR2-, and HFE-related HH. Patients with HFE HH have been divided into probands and nonprobands. Graphs show individual data points, and box and whisker plots show the median value, upper, and lower quartiles and range. Variables were compared using the Kruskal-Wallis and Dunn’s multiple comparison tests. Statistically significant differences are denoted as (a) compared with HJV, (b) compared with HAMP, (c) compared with TFR2, and (d) compared with HFE proband.