P4HA2 promotes DLBCL progression. (A) Upregulation of P4HA2 in DLBCL. Immunohistochemical analysis of P4HA2 and p-Erk in 205 DLBCL tissue samples and 20 reactive hyperplastic lymph node control samples. Hematoxylin and eosin stain; scale bar, 25 µM. (B) The OS with different expression levels of P4HA2 in DLBCL. Kaplan-Meier OS analysis of DLBCL based on low (n = 77) and high (n = 26) expression of P4HA2. Low, low expression of P4HA2, IHC 0-1; high, high expression of P4HA2, IHC 2-3. (C-E) Prognostic values of P4HA2 expression using Kaplan-Meier analysis. The OS of non-GCB subtype DLBCL (C), CHOP treatment (D), or CHOP/R-CHOP (E) treatment DLBCL based on different expression levels of P4HA2.