Kaplan-Meier survival curves of ATL cell–bearing NOG mice treated with BAY 1143572 or vehicle. Mice were treated by oral application of 12.5 mg/kg BAY 1143572 or vehicle (n = 7 for both), once daily for 21 days (7-27 days after ATL cell inoculations). The difference between the BAY 1143572 and vehicle-treated mice was statistically significant (P < .001).