Figure 2.
![Figure 2. Cumulative incidence of leukemia is delayed in the p50−/−;TCL1 mice. All experiments were carried out under protocols approved by The Ohio State University Institutional Animal Care and Use Committee. (A) A competing risks model was used to assess the occurrence of B-cell leukemia. The p50−/−;TCL1 mice had a significantly lower incidence of leukemia compared with p50+/+;TCL1 mice (subdistribution hazard ratio [SHR] for p50+/+ vs p50−/− = 3.53; 95% CI, 1.28, 9.72; P = .015). (B) The overall log-rank P value among the 3 genotypes was calculated and Kaplan-Meier estimates of the survival function are presented.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/130/3/10.1182_blood-2017-01-761130/4/blood761130f2.jpeg?Expires=1722416427&Signature=VTImyhR4xm7qug3JJVODh0A7zigZiaJ5MwK1Ff4PYOz2zGk945r1t5tpBPmHDeWuktrEbClWsddU3yhdr4pUPlb-3~k9y3SVg8E01sJCCeGQcxl3Z4EkTcSQrnDB72lrf9HZGnU24993aH2e4QUtygBr9pQQQJ~ljTyzuyy5Xvyi5Xq6aQchmqBYpOharNFHXz~bIuBrHM8xfDO7vEU7DPZtlu21INXHpHbbh37t3xWAq8ZuTtNPptwg~CMiNAkTyd-ExRwRnzQbdOaK-Rr7a~qeiNokNQzCv19vBoAYz2NZou731fOttMHsA8pnYVZCvSz87oySO8GovlMBdlWZ9w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Cumulative incidence of leukemia is delayed in the p50−/−;TCL1 mice. All experiments were carried out under protocols approved by The Ohio State University Institutional Animal Care and Use Committee. (A) A competing risks model was used to assess the occurrence of B-cell leukemia. The p50−/−;TCL1 mice had a significantly lower incidence of leukemia compared with p50+/+;TCL1 mice (subdistribution hazard ratio [SHR] for p50+/+ vs p50−/− = 3.53; 95% CI, 1.28, 9.72; P = .015). (B) The overall log-rank P value among the 3 genotypes was calculated and Kaplan-Meier estimates of the survival function are presented.
