Figure 2.
![Cumulative incidence of leukemia is delayed in the p50−/−;TCL1 mice. All experiments were carried out under protocols approved by The Ohio State University Institutional Animal Care and Use Committee. (A) A competing risks model was used to assess the occurrence of B-cell leukemia. The p50−/−;TCL1 mice had a significantly lower incidence of leukemia compared with p50+/+;TCL1 mice (subdistribution hazard ratio [SHR] for p50+/+ vs p50−/− = 3.53; 95% CI, 1.28, 9.72; P = .015). (B) The overall log-rank P value among the 3 genotypes was calculated and Kaplan-Meier estimates of the survival function are presented.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/130/3/10.1182_blood-2017-01-761130/4/blood761130f2.jpeg?Expires=1721624575&Signature=pkLibfYjxUhH1uyg-JW66xLPrDdF4hq0r57~uMDtAJd0hhofBUinXdJQ6wdn6koUCGwBXpJG~jaonfwNzILIAiqgX-E8l8XRwe4ca99oc7UM-umlx6iEhtvw4bE2gia~sSqnOrUvMSEh3qOBGRJnQjzwV6apdeoCFbGOnX0CzapOEp~bGf9jGBI6NuG6uZEvKDjF81BeO6-tAQtj9lwHUwo0tuIloXXYj0Yx~oUxHJD19kwCEI-ArK1KlMvfFTdrEMG5nKPqGaCT~8LBX7qDBCyde8Io02DRzKIB77WaK9ybvfCH1feINOiBqfxN~TH3Ni9HXzPHsjE~13Px6b1Lcw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Cumulative incidence of leukemia is delayed in the p50−/−;TCL1 mice. All experiments were carried out under protocols approved by The Ohio State University Institutional Animal Care and Use Committee. (A) A competing risks model was used to assess the occurrence of B-cell leukemia. The p50−/−;TCL1 mice had a significantly lower incidence of leukemia compared with p50+/+;TCL1 mice (subdistribution hazard ratio [SHR] for p50+/+ vs p50−/− = 3.53; 95% CI, 1.28, 9.72; P = .015). (B) The overall log-rank P value among the 3 genotypes was calculated and Kaplan-Meier estimates of the survival function are presented.
