Prevalence of DNMT3A and TET2 somatic mutation in the cohort in function of age. (A) When considering the mutations as a categorical end point (0/1), effect of 1 year increase in age on the increase in the odds of having a mutation in DNMT3A and TET2. (B) Age of the individuals harboring a DNMT3A (red, n = 215) or TET2 (blue, n = 122) somatic mutations in the cohort. The pale shading represents 95% confidence interval; ⁠, standardized regression coefficient; StdErr., standard error.