Forest plot of PFS among patient subgroups defined by cytogenetic abnormalities, including post hoc analyses of different cutoff values for individual abnormalities. *del(17p) subgroup includes patients with del(17p) alone or in combination with t(4;14) or t(14;16); t(4;14) subgroup includes patients with t(4;14) alone; amp 1q21 subgroup includes patients with amp 1q21 alone.