Genes associated with super-enhancers and sensitive to THZ1 in ATL cells. (A) Schematic of the selection criteria. (B) Super-enhancer status at 20 gene loci in Jurkat, normal T cells (thymus, Th1, Th2, and Th17), and ATL cells (TL-Om1 and 10 primary ATL samples) (left). Super-enhancers are shown in red. A heat map represents the relative expression levels of the 20 genes after THZ1 treatment in TL-Om1 cells (right). Each row corresponds to a gene.