CTL019 cellular kinetics. CTL019 cellular kinetics from a representative profile from a patient with pediatric B-ALL showing the initial expansion phase to day 28 (A) and day 780 (B). (C) Time course of levels of CTL019 transgene by qPCR and %CD3⁺ CTL019⁺ by flow cytometry for 3 patient groups: adult ALL, CLL, and pediatric B-ALL. LLOQ, lower limit of quantitation. CR/CRi, blue lines; PR/PRi, gold lines; NR/PD, red lines.