Overall survival according to dFLC 50 mg/L in the different cardiac stages. (A) Overall survival according to dFLC 50 mg/L in patients in Mayo stage I (P = .029). In the low-dFLC cohort (N = 75), median survival was not reached. In the high-dFLC cohort (N = 112), median survival was 89 months. (B) Overall survival according to dFLC 50 mg/L in Mayo stage II patients (P < .001). In the low-dFLC cohort (N = 98), median survival was 96 months. In the high-dFLC cohort (N = 364), median survival was 38 months. (C) Overall survival according to dFLC 50 mg/L in stage III patients (P = .015). In the low-dFLC cohort (N = 30), median survival was 43 months. In the high-dFLC cohort (N = 390), median survival was 6.6 months.