Prognostic impact of TP53 aberrations. Kaplan-Meier estimates of OS, PFS, and CIR according to the presence of the either TP53 aberrations (deletions and/or mutations) compared with WT TP53 (A-C), and stratified into 4 groups by the presence or absence of TP53 deletions and mutations, respectively (D-F). P values indicate log-rank tests of adjacent curves. NS, not significant.