Figure 2.
Figure 2. SD in patient UPN33 during (arrows) and after WT1/DC vaccination. WT1 transcript levels (determined by the Ipsogen WT1 ProfileQuant Kit) in blood (A) and bone marrow (B) were above background (indicated by the dotted blue line) but remained stable, and the bone marrow blast count normalized (normal value indicated by the dotted pink line). (C) Blood values showed pancytopenia at the start of DC vaccination but a normal hemoglobin level (without transfusions) at the end of the SD period (at 19 months); neutropenia was treated with granulocyte colony-stimulating factor. 4 × biw + DTH, period of the first 4 biweekly WT1/DC vaccinations and DTH; ANC, absolute neutrophil count; CTx (I + C), polychemotherapy (induction + 2 consolidations).

SD in patient UPN33 during (arrows) and after WT1/DC vaccination.WT1 transcript levels (determined by the Ipsogen WT1 ProfileQuant Kit) in blood (A) and bone marrow (B) were above background (indicated by the dotted blue line) but remained stable, and the bone marrow blast count normalized (normal value indicated by the dotted pink line). (C) Blood values showed pancytopenia at the start of DC vaccination but a normal hemoglobin level (without transfusions) at the end of the SD period (at 19 months); neutropenia was treated with granulocyte colony-stimulating factor. 4 × biw + DTH, period of the first 4 biweekly WT1/DC vaccinations and DTH; ANC, absolute neutrophil count; CTx (I + C), polychemotherapy (induction + 2 consolidations).

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