Mutation landscape of enrolled patients. (A) Frequency of detected mutations based on World Health Organization 2016 subtype. MDS-EB, MDS with excess blasts; MDS-MLD, MDS with multilineage dysplasia; MDS/MPN-U, MDS/MPN unclassifiable; MDS-SLD, MDS with single lineage dysplasia. Frequencies are expressed for total number of patients studied for each particular mutation. (B-C) Circos plot and table describing frequencies of identified mutations based on treatment group.