Treatment-emergent AEs (by preferred term) reported in ≥15% of patients in the DLT-evaluable population, regardless of attribution. Each AE was counted only once per patient, regardless of the number of events observed in an individual patient. Events are rank ordered by overall frequency, and maximum event grade is displayed. *AEs were coded by preferred term by the reporting investigator according to MedDRA, which includes edema and peripheral edema.