lncRNAs can interfere with miRNA function in AML. A picture depicting the ways lncRNAs can affect miRNA biology in AML, including (1) lncRNAs serving as a source for mature miRNA production, (2) lncRNAs acting as miRNA sponges, binding miRNAs to prevent them from repressing their target mRNAs, and (3) altering miRNA gene transcription.