Zeb2 is dispensable for self-renewal. (A) Schematic of the transplant and analysis setting. (B) Analysis of peripheral blood (PB) cells at 16 weeks posttransplant show significantly fewer WBCs and their subsets, thrombocytes and erythrocytes, in Zeb2^Δ/ΔMx1-Cre BM recipients compared with their WT counterpart. (C) Schema of a competitive BM transplant. (D) The relative contribution of donor, competitor, and remaining recipient-derived blood cells in reconstituted recipients at 16 weeks after transplant reveals a significantly reduced contribution of Zeb2^Δ/ΔMx1-Cre–derived cells in most lineages.