SMGs in FL. The frequency and type of mutations affecting 39 genes identified as significantly mutated in our cohort using MuSiC analysis (FDR < 0.05, convolution test method) are displayed in each row. Columns represent each patient in the cohort and are ordered by the presence of mutations in the most to least frequently mutated gene. The bar graph on the left corresponds to the frequency of mutations for that gene in the entire cohort. For genes with multiple mutations in a single patient, only 1 mutation type is shown with priority order indicated in the legend from the highest priority at the top to lowest at the bottom. For individuals with multiple samples, the union of mutations in all samples for that individual was used. The mutation waterfall plot was created using the “GenVisR” package in R.⁴¹