Figure 1.
Kinase interaction maps. Shown here are the maps for 5 small-molecule kinase inhibitors ranging from very nonselective (staurosporine) to highly selective (quizartinib). The black arrow on each dendrogram denotes the approximate location for the FLT3 receptor. Lestaurtinib, midostaurin, sorafenib, and quizartinib have all been studied as FLT3 inhibitors. Adapted from Davis et al26 with permission.
