Figure 1.
Figure 1. Immunoglobulin variable region gene usage in systemic and localized amyloidosis. KV1-other: includes rare KV1-genes (KV1-02, 06, 08, 09, 12, 13, 17, and 27) and cases where only KV1 family could be determined. Other κ/λ: includes rare κ genes (n = 8, KV2-28, 30, 38, KV3-01, 07, 11, KV6-21, rare KV1 excluded because included in KV1-other); rare λ genes (n = 29, LV1-01, 36, 52, 57, LV2-08, 11, 18, LV3-09, 10, 20, 25, LV4-60, 69, and LV10-54), cases where only family could be determined (n = 49); IGKC and IGLC: cases that no gene or family could be determined (n = 86). HC, non-IgG heavy chain. *P < .05, **P < .01, ***P < .001.

Immunoglobulin variable region gene usage in systemic and localized amyloidosis.KV1-other: includes rare KV1-genes (KV1-02, 06, 08, 09, 12, 13, 17, and 27) and cases where only KV1 family could be determined. Other κ/λ: includes rare κ genes (n = 8, KV2-28, 30, 38, KV3-01, 07, 11, KV6-21, rare KV1 excluded because included in KV1-other); rare λ genes (n = 29, LV1-01, 36, 52, 57, LV2-08, 11, 18, LV3-09, 10, 20, 25, LV4-60, 69, and LV10-54), cases where only family could be determined (n = 49); IGKC and IGLC: cases that no gene or family could be determined (n = 86). HC, non-IgG heavy chain. *P < .05, **P < .01, ***P < .001.

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