Figure 1.
Figure 1. Scatterplots of expression levels: receiver-operating characteristics curve analyses. (A-C) Scatter plots of expression levels. Scatter plots of expression levels of miR-92 (A), miR-19b (B), and miR-21 (C) in vitreous samples from patients with PVRL (n = 10) compared with subgroups of patients with vitritis (n = 40), and noninflammatory macular pucker patients (n = 10). The black horizontal lines represent median REL values. Group-wise, P values are indicated as determined in Kruskal-Wallis tests with Dunn multiple comparisons (*P < .05). (D-E) Receiver-operating-characteristics curve analyses. Receiver-operating-characteristics curve analyses with RELs of vitreous miRNAs for discrimination of patients with PVRL (n = 10) and vitritis patients (n = 40). Vitreous relative expression of miR-92 yielded an AUC of 0.9725 (95% confidence interval [CI], 0.9340-1.011) (D), for miR-19b an AUC of 0.9400 (95% CI, 0.8555-1.024) (E), and for miR-21 an AUC of 0.8125 (95% CI, 0.6723-0.9527) (F), respectively.

Scatterplots of expression levels: receiver-operating characteristics curve analyses. (A-C) Scatter plots of expression levels. Scatter plots of expression levels of miR-92 (A), miR-19b (B), and miR-21 (C) in vitreous samples from patients with PVRL (n = 10) compared with subgroups of patients with vitritis (n = 40), and noninflammatory macular pucker patients (n = 10). The black horizontal lines represent median REL values. Group-wise, P values are indicated as determined in Kruskal-Wallis tests with Dunn multiple comparisons (*P < .05). (D-E) Receiver-operating-characteristics curve analyses. Receiver-operating-characteristics curve analyses with RELs of vitreous miRNAs for discrimination of patients with PVRL (n = 10) and vitritis patients (n = 40). Vitreous relative expression of miR-92 yielded an AUC of 0.9725 (95% confidence interval [CI], 0.9340-1.011) (D), for miR-19b an AUC of 0.9400 (95% CI, 0.8555-1.024) (E), and for miR-21 an AUC of 0.8125 (95% CI, 0.6723-0.9527) (F), respectively.

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