CD34⁺HSPC mobilization and plerixafor PKs. (A) Mobilization of CD34⁺ cells to the peripheral blood over time from donors in phase 1 portion of the trial. (B) PK levels of plerixafor measured in blood over time in phases 1 and 2. (C) Summary of mobilization data of CD34⁺ cells over time in donors treated with IV and SC plerixafor. SC mobilization results were obtained from phase 1 of this study and IV data from phase 1 and 2 trials.