Figure 5.
Figure 5. Selective increase of PD-1 expression on CD45RA– activated-memory Tregs in patients with cGVHD receiving low-dose IL-2. (A) Representative flow cytometry histograms used to define CD4 T-cell subsets. (B) Median percentages of PD-1+ cells in Tcon and Treg subsets during IL-2 therapy; CD45RA– activated-memory Tregs vs baseline using Wilcoxon signed rank test. *P < .05, **P < .01.

Selective increase of PD-1 expression on CD45RA–activated-memory Tregs in patients with cGVHD receiving low-dose IL-2. (A) Representative flow cytometry histograms used to define CD4 T-cell subsets. (B) Median percentages of PD-1+ cells in Tcon and Treg subsets during IL-2 therapy; CD45RA– activated-memory Tregs vs baseline using Wilcoxon signed rank test. *P < .05, **P < .01.

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