Figure 1.
High ST2 and TIM3 are associated with NRM by 2 years. (A) Absolute values on a logarithmic scale for ST2 and TIM3 at days 28, 100, and 180 with their medians and interquartile range, P < .01 for all comparisons except for TIM3 on day 100 (P = .037). (B) ROC curve for NRM by 2 years with AUC for post-HCT day 28 ST2, IL-6, Reg3α, TIM3, the 4 biomarkers combined, and clinical covariates in the combined model. The biomarker panel improves the AUC from 0.74 for the clinical covariates to 0.80 in the combined model. N, patients who did not die from NRM; Y, patients who died from NRM.

High ST2 and TIM3 are associated with NRM by 2 years. (A) Absolute values on a logarithmic scale for ST2 and TIM3 at days 28, 100, and 180 with their medians and interquartile range, P < .01 for all comparisons except for TIM3 on day 100 (P = .037). (B) ROC curve for NRM by 2 years with AUC for post-HCT day 28 ST2, IL-6, Reg3α, TIM3, the 4 biomarkers combined, and clinical covariates in the combined model. The biomarker panel improves the AUC from 0.74 for the clinical covariates to 0.80 in the combined model. N, patients who did not die from NRM; Y, patients who died from NRM.

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