Aid loss causes myeloid expansion and anemia in vivo. (A) PB samples were collected from WT, Aid^+/−, and Aid^−/− adult mice around 8 weeks old. White blood cell (WBC) counts, RBC counts, Hb levels, HCT percentages, and platelet counts were measured. The data are mean ± SD (WT and Aid^+/−; n = 3, Aid^−/−; n = 4). (B) Representative immunophenotype of BM granulocyte/monocyte lineage (Mac1/Gr1), erythroid lineage (CD71/Ter119), myeloid progenitors (Lineage⁻IL7Ra⁻Sca1⁻cKit⁺), and common myeloid progenitors (CMPs)/GMPs/MEPs derived from WT, Aid^+/−, and Aid^−/− adult mice around 8 weeks old. MP, myeloid progenitor; N.S., not significant; PLT, platelet.