Figure 5.
Figure 5. Many endogenous myeloid progenitors are replaced by donor myeloid progenitors upon the transplantation of HSCs into unconditioned mice. Unconditioned CD45.1 × CD45.2 recipients were transplanted with 2.5 × 105 purified CD45.2 HSCs. Bone marrow was analyzed for the numbers of total nucleated cells (A) and donor (CD45.2+), endogenous (CD45.1+CD45.2+), and total GMPs (B) 13 weeks after transplantation (n = 3). All error bars represent standard deviations of the means.

Many endogenous myeloid progenitors are replaced by donor myeloid progenitors upon the transplantation of HSCs into unconditioned mice. Unconditioned CD45.1 × CD45.2 recipients were transplanted with 2.5 × 105 purified CD45.2 HSCs. Bone marrow was analyzed for the numbers of total nucleated cells (A) and donor (CD45.2+), endogenous (CD45.1+CD45.2+), and total GMPs (B) 13 weeks after transplantation (n = 3). All error bars represent standard deviations of the means.

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