Sin3B^CKOHSCs are myeloid biased. Percent of B (B220⁺), T (CD4⁺ or CD8⁺), and myeloid (CD11b⁺) cells from donor-derived peripheral blood in primary (A) and secondary (B) recipient animals 20 weeks after transplantation. (C) Representative FACS plot of CD150 surface staining of LT-HSCs of indicated genotypes. (D) Quantification of percentage of CD150^HIGH, CD150^LOW, and CD150^NEG within the LT-HSC population; n ≥ 8. Data are represented as mean ± SEM. *P < .05; **P < .01. NS, not significant.