GEP analysis in DLBCL. (A) Heatmap for GEP comparison between CD37⁺ and CD37⁻ DLBCL (FDR, <0.05). (B) The KEGG chemokine signaling pathway gene set was enriched in the CD37⁻ DLBCL group with an enrichment score of 0.45 (FDR, 0.09). (C) The KEGG phagosome gene set was enriched in CD37⁻ ABC-DLBCL with an enrichment score of 0.55 (FDR, 0.006). (D) Heatmap for GEP comparison between CD37⁺ ABC-DLBCL and CD37⁻ ABC-DLBCL groups with high (≥70%) PI3K expression (FDR, <0.01). (E) Heatmap for genes differentially expressed between GCB and ABC subtypes of CD37⁻ DLBCL with more than twofold difference (FDR, <0.01). (F) Heatmap for genes differentially expressed between GCB and ABC subtypes of CD37⁺ DLBCL with >2.4-fold difference (FDR, < 0.01).