Figure 4.
Figure 4. Relationship between expression levels of ROR1, TFS, and OS. Patients in the training cohort were segregated into ROR1-Lo vs ROR1-Hi subgroups using the ROR1 ΔMFI threshold found optimal for defining 2 groups that had the largest difference in TFS, whereas patients in the validation cohort were segregated into 2 subgroups using the ROR1 ΔMFI threshold found optimal for cases in the training cohort. (A-B) Kaplan-Meier curves depict the TFS probability over time for ROR1-Lo (dashed line) vs ROR1-Hi (continuous line) subgroups in the training cohort (A) or validation cohort (B). (C-D) Kaplan-Meier curves depict the OS probability over time for ROR1-Lo (dashed line) vs ROR1-Hi (continuous line) subgroups in the training cohort (C) or validation cohort (D). The number of patients in each category and the number of treatment events are shown in the tables under each figure. Statistical significance was determined by log-rank test (P < .05). The P values for the comparisons between subgroups are indicated below each graph.

Relationship between expression levels of ROR1, TFS, and OS. Patients in the training cohort were segregated into ROR1-Lo vs ROR1-Hi subgroups using the ROR1 ΔMFI threshold found optimal for defining 2 groups that had the largest difference in TFS, whereas patients in the validation cohort were segregated into 2 subgroups using the ROR1 ΔMFI threshold found optimal for cases in the training cohort. (A-B) Kaplan-Meier curves depict the TFS probability over time for ROR1-Lo (dashed line) vs ROR1-Hi (continuous line) subgroups in the training cohort (A) or validation cohort (B). (C-D) Kaplan-Meier curves depict the OS probability over time for ROR1-Lo (dashed line) vs ROR1-Hi (continuous line) subgroups in the training cohort (C) or validation cohort (D). The number of patients in each category and the number of treatment events are shown in the tables under each figure. Statistical significance was determined by log-rank test (P < .05). The P values for the comparisons between subgroups are indicated below each graph.

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