Prognostic impact of key HLA and KIR genotypes emerging from multivariate analysis. Adjusted (A-B and C-D) and unadjusted (E-F and G-H) 1-year probabilities of relapse and OS in the discovery vs validation cohorts according to HLA and KIR genotype. Patients in each cohort were classified into 3 categories: HLA-C1/x receiving an HLA-C1-KIR2DL2/L3/S2 graft (red line), HLA-C1/x receiving an HLA-C1-KIR2DL2/L3/S2 graft (green line), and HLA-C2 homozygous patients (purple line).