Cellular infiltration in the IgE-CAI skin lesion is decreased in mMCP-11–deficient mice. WT and KO mice were treated as in Figure 2 to induce IgE-CAI. (A) Photomicrographs show hematoxylin and eosin–stained specimens of IgE-CAI skin lesions on day 3 postchallenge. Scale bars, 200 μm. (B-C) Graphs show the numbers of cells of each indicated cell type that were isolated from the TNP-OVA–treated ear skin (black bars) or control OVA–treated ear skin (gray bars) on day 3 postchallenge (mean ± SD, n = 5 or 6 ears each). Data shown are representative of 3 independent experiments. *P < .05; **P < .01; Mo-Mac, monocytes/macrophages.