Epo induction in NG2-Vhl^−/− mice is cell autonomous. (A) Shown are individual Hcts, RBC, and Hb values for Cre⁻ control and in NG2-Vhl^−/−Epo^−/− mice (n = 8-10). Bar graphs show serum EPO levels (sEPO) for Cre⁻ and NG2-Vhl^−/−Epo^−/− mice (n = 5-7). (B) Striatal (ST), hypothalamic (HYT), cortical (CTX), and hippocampal (HP) Epo mRNA levels in Cre⁻ and NG2-Vhl^−/−Epo^−/− mice (n = 4 each). Data are represented as mean ± SEM; 2-tailed Student t test; *P < .05 compared with Cre⁻ control group.