Atorvastatin reduced phospho-p38 MAPK activity in cultivated BM EPCs from PGF subjects. The cultivated BM EPCs from PGF subjects were incubated with atorvastatin (500 nM). Phospho-p38 (A) and phospho-CREB (B) expression was analyzed by flow cytometry in the cultivated BM EPCs at day 7 in culture. Data are expressed as the MFI (mean ± SEM). (C) Representative western blots of phospho-p38, total p38, and GADPH from cultivated BM EPCs at day 7 in culture among subjects with PGF, subjects with GGF, and normal controls.