In vitro treatment with atorvastatin, p38 inhibitors, and ROS inhibitor demonstrated similar effects on the number and function of cultivated BM EPCs from PGF subjects. The cultivated BM EPCs from PGF subjects were incubated with atorvastatin (500 nM), NAC (1 mM), SB203580 (10 μM), or BIRB796 (400 nM). The effects of the different treatments on cell number (per well) (A), cell proliferation (B), double positive staining cells (per well) (C), migration (D), tube formation (E), apoptosis (F), and ROS levels (G) of cultivated BM EPCs from PGF subjects were compared at day 7 in culture. Data are expressed as fold-change relative to PGF.