Figure 2.
Figure 2. Schematic representation of the N-linked glycosylation sites and the most frequently identified glycans attached to each site. The glycan structures were determined using the workflow described in supplemental Figure 2. (A) Schematic representation of the glycans identified on ADAMTS13. Each glycan is attached to the corresponding domain. (B) Glycan composition, amino acid position, and corresponding domain of ADAMTS13. There is one glycan on pADAMTS13 that was only identified with a high mannose structure; the remaining glycosylation sites were predominantly identified with complex structures terminating in sialic acid; 6 of 10 glycans were fucosylated.

Schematic representation of the N-linked glycosylation sites and the most frequently identified glycans attached to each site. The glycan structures were determined using the workflow described in supplemental Figure 2. (A) Schematic representation of the glycans identified on ADAMTS13. Each glycan is attached to the corresponding domain. (B) Glycan composition, amino acid position, and corresponding domain of ADAMTS13. There is one glycan on pADAMTS13 that was only identified with a high mannose structure; the remaining glycosylation sites were predominantly identified with complex structures terminating in sialic acid; 6 of 10 glycans were fucosylated.

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